Abstract: lntroduction: Ocular lesions of Behcet's Disease (BD) need aggressive treatment to prevent from severe loss of vision or blindness. Cytotoxic drugs are necessary for the treatment. A short-term study with azathioprine (AZA) was presented to the 8th lnternational Conference on Behcet's Disease. The aim of this study is to present the results for a longer period of time. Materials & methods: Patients (32) who received more than 9 months of treatment ...
Abstract: Introduction: The ocular lesions of Behcet's disease (BD) progress usually toward severe loss of vision or blindness, and therefore need aggressive treatment. However, even such a treatment is not always successful. We used classification and regression tree (cart) method to see if some factors could predict the result of the future treatment. Methods: Eight hundreds and thirty patients who fulfilled the Iran criteria for BD were selected for this study. They ...
Abstract: Objective: Systemic sclerosis is a generalized disorder of connective tissue disease. This study surveyed the clinical manifestations of systemic sclerosis in early (6 years) phases of limited and diffuse variants. Methods: Nineteen patients with diffuse and thirty-four cases with limited form of disease were selected consecutively from 1992 to 1998. Sixty-five clinical data were evaluated and then analyzed by MC-Nemar chi square test between two forms in both phases. Results: (1) There were ...
Abstract: The neuropsychiatric manifestations of systemic lupus erythematosus are frequent. One of the most serious presentations is convulsion. This study was carried out to evaluate the relation between convulsion and anti-DNA antibody levels. An analytic, retrospective case-controlled study was carried out, with reference to 1001 recorded cases of systemic SLE lupus erythematosus in Lupus Unit, Rheumatology Center, Shariati Hospital, Tehran University of Medical Sciences. The frequency Of convulsion was 13.3%. There ...
Abstract: Objective: To assess the course of maternal disease and outcome of pregnancy in patients with systemic lupus erythematosus (SLE). Patients and Methods: One hundred SLE patients who carried out 128 pregnancies were studied retrospectively. These patients were followed in lupus unit every one to two months by the rheumatologist and obstetrician team throughout pregnancy. Some patients were given prophylactic low-dose Prednisolone. Lupus flares were treated by increasing Prednisolone doses. Patients who ...
Abstract: Objective: Exercises, especially sports have an effective role in increasing of Bone Mineral Density (BMD). This study surveyed the bone density in athlete women compared to Iranian standard BMD at the same age and sex. Methods: This study was a prospective survey on thirty-nine athlete women between 20 to 30 years old. Subjects were selected randomly in six different athletes groups including basketball, volleyball, tennis, badminton, swimming and running. BMD was measured ...
Abstract: Introduction: Posterior uveitis (PU) and retinal vasculitis (RV) are the main morbidity factor in Behcet’s Disease (BD). They usually progress toward severe loss of vision or blindness. They need aggressive treatment with cytotoxic drugs. Azathioprine was demonstrated, in a double blind control study, to be effective in Behcet’s Disease. The aim of this study was to evaluate the efficacy of Azathioprine in ocular lesions of BD, and to compare ...
Abstract: The bone mass density (BMD) may vary in different countries due to different genetic and environmental factors. This study was performed to determine the BMD of the normal population in Iran. Subjects were selected randomly from different social workers classes in Tehran (from the lowest to the highest). For each decade and sexes, 20 normal subjects were selected (140 men and 140 women). BMD was measured with a Hologic 1000 ...
Abstract: Introduction: Behcet's disease (BD) is a multisystem disease characterized by recurrent oral and genital ulcers, skin and ocular lesions. Other organ involvement occurs as minor manifestations of the disease. Cardiac involvement is not a common feature of the disease, but may be a sign for poor prognosis. The exact prevalence of cardiac involvement is not exactly known, only selected cases are reported in the literature. Our study .was designed to ...
Abstract: Introduction: Cytotoxic drugs are all effective in the treatment of ocular lesions of Behcet’s disease (BD). However, with all methods there are some patients that their eye lesions will progress despite the treatment. This study was designed to find whether a combination therapy with 2 of these drugs could have better effect in reducing the rate of non-responders. Materials & Methods: Twenty eight patients diagnosed as BD (according to the Iran ...